A neuron's excitability is determined by the distribution of ion channels along its membrane. Diverse neurological disorders, such as autism, epilepsy, and developmental delays, are caused by disruptions of these channels. Dr. Ben-Shalom combines electrophysiology and neuronal modeling to advance the understanding of these diseases. In order to reverse engineer neuronal excitability in health and disease, Ben-Shalom's lab incorporates the biophysical properties of single neurons into detailed numerical models. In addition to facilitating an understanding of the pathophysiology of neurodevelopmental disorders, these models can also serve as testing grounds for therapeutic interventions.

Accepting students per funding availability.