BME team publish in Science Signaling

Rafael Shimkunas, 2nd-year PhD student in the BME Graduate Group, has published his first co-authored paper at UC Davis in the journal Science Signaling: In the paper, which is featured on the cover of the issue, Rafael and Chen-Izu Lab colleagues used a novel hydrogel system to investigate the mechano-chemotransduction mechanisms in cardiac myocytes. They discovered mechanical stretch applied to cells activates nNOS signaling and contributes to aberrant calcium sparks that can lead to arrhythmia and heart failure.

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